Increased Metabolic Rate in X-linked Hypophosphatemic Mice

Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice. This led to the search for some alteration in metabolism in Hyp mice. We found that oxygen consumption was significantly higher in Hyp mice than in normal C57BL/6J mice and this was accompanied by an increased percentage of cardiac output being delivered to organs of heat production (liver and skeletal muscle), to the skin, and to bone and a decreased percentage to the gastrointestinal tract of Hyp mice. The increased oxygen consumption in Hyp mice was not associated with increased plasma free T4 levels and was not affected by alterations in plasma phosphate produced by a low phosphate diet. The cause of the increased oxygen consumption is not known, and the role that this change and reported changes in distribution of cardiac output may play in the development of X-linked hypophosphatemia is also unknown. Study of the cardiovascular and thermoregulatory systems in Hyp mice should help increase understanding of the underlying mechanisms of this disease

Lattice Gauge Theory Sum Rule for the Shear Channel

An exact expression is derived for the $(\omega,p)=0$ thermal correlator of shear stress in SU($N_c$) lattice gauge theory. I remove a logarithmic divergence by taking a suitable linear combination of the shear correlator and the correlator of the energy density. The operator product expansion shows that the same linear combination has a finite limit when $\omega\to\infty$. It follows that the vacuum-subtracted shear spectral function vanishes at large frequencies at least as fast as $\alpha_s^2(\omega)$ and obeys a sum rule. The trace anomaly makes a potential contribution to the spectral sum rule which remains to be fully calculated, but which I estimate to be numerically small for $T\gtrsim 3T_c$. By contrast with the bulk channel, the shear channel spectral density is then overall enhanced as compared to the spectral density in vacuo.Comment: 11 pages, no figure

Listeners normalize speech for contextual speech rate even without an explicit recognition task

Speech can be produced at different rates. Listeners take this rate variation into account by normalizing vowel duration for contextual speech rate: An ambiguous Dutch word /m?t/ is perceived as short /mAt/ when embedded in a slow context, but long /ma:t/ in a fast context. Whilst some have argued that this rate normalization involves low-level automatic perceptual processing, there is also evidence that it arises at higher-level cognitive processing stages, such as decision making. Prior research on rate-dependent speech perception has only used explicit recognition tasks to investigate the phenomenon, involving both perceptual processing and decision making. This study tested whether speech rate normalization can be observed without explicit decision making, using a cross-modal repetition priming paradigm. Results show that a fast precursor sentence makes an embedded ambiguous prime (/m?t/) sound (implicitly) more /a:/-like, facilitating lexical access to the long target word "maat" in a (explicit) lexical decision task. This result suggests that rate normalization is automatic, taking place even in the absence of an explicit recognition task. Thus, rate normalization is placed within the realm of everyday spoken conversation, where explicit categorization of ambiguous sounds is rare

Time-Temperature Superposition of Structural Relaxation in a Viscous Metallic Liquid

Bulk metallic glass-forming Pd40Ni10Cu30P20 has been investigated in its equilibrium liquid by quasielastic neutron scattering. The quasielastic signal exhibits a structural relaxation as known from nonmetallic viscous liquids. Even well above the melting point, the structural relaxation is nonexponential and obeys a universal time-temperature superposition. From the mean relaxation times average diffusivities have been determined, resulting in values on a 10^-10 m^2 s^-1 scale, 3 orders of magnitude slower than in simple metallic liquids

Modification and improvements to cooled blades Patent

Modification and improvement of turbine blades for maximum cooling efficienc

Integrability of the critical point of the Kagom\'e three-state Potts mode

The vicinity of the critical point of the three-state Potts model on a Kagom\'e lattice is studied by mean of Random Matrix Theory. Strong evidence that the critical point is integrable is given.Comment: 1 LaTex file + 3 eps files 7 page

The Effects of the Minimum Wage on the Employment and Earnings of Youth

The employment and earnings effects of the minimum wage are estimated by parameterizing an hypothesized relationship between underlying market employment and wage relationships versus observed wage and employment distributions in the presence of a legislated minimum. If there had been no minimum during the 1973-78 period, we estimate that employment among out- of-school men 16 to 24 would have been approximately 4 percent higher than it in fact was. Among young men 16 to 19 employment would have been about 7 percent higher and among those 20 to 24, 2 percent higher. Employment among black youth 16 to 24 would have been almost 6 percent higher than it was, as compared with somewhat less than 4 percent for white youth. Although it is sometimes argued that the adverse employment effects of the minimum are offset by increased earnings, we find virtually no earnings effect. Had the minimum not been raised over the 1973-78 period, inflation would have greatly moderated the adverse employment effects of the minimum, with approximately two-thirds of the potential employment gains from elimination of the minimum attained. The weight of our evidence is inconsistent with a general increase in youth wage rates with increases in the real minimum. Our findings support the hypothesis that the effects of the minimum are concentrated on youth with sub-minimum market wage rates.